Tacrolimus is a calcineurin inhibitor used as compounded ophthalmic drops to treat KCS and immune-mediated conditions like pannus. It suppresses the immune response destroying tear-producing glands โ€” treating the cause, not just symptoms.

๐Ÿ’ก Many vets prefer compounded tacrolimus for dogs who don’t respond to cyclosporine. Studies show 65โ€“80% response in cyclosporine-refractory KCS within 8โ€“12 weeks.

Standard Dose 1 drop per affected eye, twice daily (BID)
Onset Improvement typically within 4โ€“6 weeks
Maintenance Most dogs require lifelong treatment
If Eye Is Red Hold dose โ€” contact your vet first
๐Ÿ’ก Apply right after a meal โ€” builds a positive association for long-term compliance.

How do I place an order?
Sign in to your clinic account and use Submit Rx. New clinics are verified in under 24 hours โ€” your rep will call to confirm.
Auto-Order sends your standing order automatically on the schedule you set. Modify, pause, or cancel anytime from your dashboard.
Yes โ€” direct-to-client is our preferred workflow. Submit the Rx, your client completes checkout on PetScript Pharmacy, and we ship to them with full tracking visible to you.
Yes โ€” send your current invoice to your rep and we’ll match or beat it before your next order. No minimums, no contracts.
Compounded Ophthalmic Solution ยท 10mL ยท Requires Veterinary Prescription

Compounded tacrolimus 0.02% ophthalmic drops for treating KCS (dry eye) and immune-mediated conditions including pannus in dogs. Prepared in our USP 797-compliant sterile cleanroom and batch-tested before every shipment.

Direct-to-client shipping

48-hour turnaround standard

Price matching available

Tacrolimus is a calcineurin inhibitor used as compounded ophthalmic drops to treat KCS and immune-mediated conditions like pannus. It suppresses the immune response destroying tear-producing glands โ€” treating the cause, not just symptoms.

๐Ÿ’ก Many vets prefer compounded tacrolimus for dogs who don’t respond to cyclosporine. Studies show 65โ€“80% response in cyclosporine-refractory KCS within 8โ€“12 weeks.

Standard Dose 1 drop per affected eye, twice daily (BID)
Onset Improvement typically within 4โ€“6 weeks
Maintenance Most dogs require lifelong treatment
If Eye Is Red Hold dose โ€” contact your vet first
๐Ÿ’ก Apply right after a meal โ€” builds a positive association for long-term compliance.

How do I place an order?
Sign in to your clinic account and use Submit Rx. New clinics are verified in under 24 hours โ€” your rep will call to confirm.
Auto-Order sends your standing order automatically on the schedule you set. Modify, pause, or cancel anytime from your dashboard.
Yes โ€” direct-to-client is our preferred workflow. Submit the Rx, your client completes checkout on PetScript Pharmacy, and we ship to them with full tracking visible to you.
Yes โ€” send your current invoice to your rep and we’ll match or beat it before your next order. No minimums, no contracts.

Pricing for Verified Clinics

PetScript’s pricing is exclusively available to licensed veterinary practices. Sign in or create a free account to see pricing and place orders.

Wholesale pricing for verified clinics

Price matching available on all compounds

Free account setup โ€” no minimums

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